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  • Interesting to see TEMs have been improved to sub-ångström - the 3D reconstruction mentioned near the end of the article is particularly intriguing: wired.com/story/new-microscope…um-world-in-crazy-detail/

  • Some recent news

    Jim Logajan - - Paths

    Post

    Quote from lsuess: “Another one: "Atomic-scale manufacturing now a reality" phys.org/news/2018-05-atomic-scale-reality.html It's about this paper: "Autonomous Scanning Probe Microscopy in Situ Tip Conditioning through Machine Learning" researchgate.net/publication/3…_through_Machine_Learning I guess this needs to be combined with the R&D results which I've posted about recently here: Major improvement in STM control methodology. ” Looks promising - thanks for posting those news items. Though I f…

  • Thanks for the links and information - very helpful! The Christian Schafmeister video was very interesting. Quite a rabbit hole to go down, as he said, to get what he wanted.

  • I hope to retire mid-year from my decidedly non-nanotech related job, which will give me more time to devote to nanotech stuff. One task I'd like to do is try my hand at using some of the existing molecular modeling tools to determine their strong and weak points with respect to design of molecular machines. Probably someone has already done this, so that would be the first thing to check. As chemist Frank Westheimer once observed: "A couple of months in the laboratory can frequently save a coup…

  • Synthetic chemistry machine

    Jim Logajan - - Paths

    Post

    Saw this remotely related announcement today: Scientists create world’s first ‘molecular robot’ capable of building molecules The original article in Nature: Stereodivergent synthesis with a programmable molecular machine I say "remotely related" because it also looks to use a manufacturing system in a solution that can synthesize some kinds of molecules. But it appears to use a chemically positionable "arm" which would put it in a different class of machines/techniques than the previously menti…

  • Quote from lsuess: “I guess the one most widely known of these is the "Great Pyramid of Giza" best viewed form the perspective of "Pyramid of Menkaure". mrgris.com/projects/merc-extreme/#0b6b7dd3@29.97271,31.12854 ” A good choice - Giza was the first place I thought of when I started thinking of well known but temporally distant things. But as you note, not much interesting in its vicinity. Quote from lsuess: “Maybe: Greece Athens "Sunken Lake" (with caves unexplored to this day). en.wikipedia.o…

  • Quote from lsuess: “I found an interactive version of nonlinear mapping: mrgris.com/projects/merc-extreme/ (Tip: turn on satellite view) What would be the most visually interesting while least politically, religiously, ideologically problematic place to focus at for a screenshot demonstrating that kind of the mapping? This is already hard. Additionally asking for a place that can be easily identified by most of the worlds population is probably too much and likely leaves no results. ” "Least pro…

  • Sorry for the tardy reply. It looks like those URL pointers got messed up during the port to the new forum software. I'm not sure where the links were supposed to point. I'll do some more searching to see what I can find.

  • I did send a message to Josh via my linkedin.com contact when I started this web site. I did not hear back from him. However, I see he has a Facebook page and is active there (he just posted today in fact.) After browsing his posts, it looks like he now has a pilot license certificate - earned about 5 years ago and still flying, so medically fit to fly per the FAA. (I do not have a Facebook account, but my wife does. We jointly use hers to keep in touch with family members who joined. Neither of…

  • I did reply to Dr. Neil Sarkar saying I was interested in any information they could share. I indicated a general interest in scanning probe nanolithography since that seemed the most relevant use of their product given its resolution and what I would really attempt with such a device. I have not yet heard anything from them. I was not aware of the two efforts you found. The ISCPI AFM is about 2.6 times more expensive, but has about 40 times greater resolution, than the Stromlinet Nano AFM. I co…

  • I received a reply from the president, Dr. Neil Sarkar. I'm going to go out on a limb and assume he would have no objection to his response being published verbatim, so here it is: Hi Jim, Thank you for your interest in the nGauge AFM system, I'm happy to answer your questions (apologies for the delay). We have a conductive path to the tip in all of our AFM chips, but we do not yet support electrical modes. Our team has produced scanning microwave microscopes, which are on the product roadmap bu…

  • Appended to this post is the content of an email I sent to their info@ address. If I get a response I'll post a summary of its content here. If they don't answer by the 8th I'll try to find another way to contact them. Since the chips are essentially consumables they should have priced them well above cost to manufacture. The patents on their web site all pertain to the technology in the chips and not to the stage. The assignee for each of the six patents they mention are Niladri Sarkar, Icspi C…

  • I presume this is the firm's site (let me know if it isn't): icspicorp.com/ Obviously the price is based on their expectations of number of units they hope to sell versus the cost they've so far spent in developing the microscope plus per-unit costs. And also what competitors are charging and getting away with - even though they claimed it was for the masses. I had not previously looked at the current market for AFMs but your post made me curious and I came across the following document which gi…

  • Drexler mentions that it appears to be progressing at the speed of government. I would expect results in fifteen to twenty years, then.

  • It's an interesting building block, but I think a modest stretch to call it a breakthrough. Is there a molecular version proposed yet?

  • Welcome Diamondoid! It is difficult to say what approach will yield the quickest route, since only modest progress has been made in any of the approaches. When my time permits, I've been looking at using SPMs in the bootstrap phase. I suspect that DNA engineered bacteria are another approach that may be relatively fast. I'm not aware of anyone making any progress using any of the other techniques you mention to the extent that those two approaches have already demonstrated in the lab.

  • Quote from lsuess: “So you mean like the Nanomedicine books by Robert Freitas (I haven't yet read them)? ” Yes, something along those lines. Getting older seems to have made me more interested in nanotech applications of medicine. Quote from lsuess: “There are two more possible usages for de novo foldamer engineering (foldamer being the most general case) B) as "simple" delivery vessels for drugs C) for bootstrapping advanced APM. ” Someone is likely to prove me wrong, but I'm not sure that that…

  • Quote from lsuess: “1) I was visiting the first ever Makerfaire in Vienna Austria showing of my collection of 3D prints. I also made a lot of graphical Infosheets for A4 flipcharts about 3D printing and APM. ” Sounds interesting! Quote from lsuess: “* that the visalisation pictures of cell membranes are basically all very wrong showing way to much lipid layer and way too few proteins going through and showing the size ratios very wrong too. ” Yes, the high percentage of membrane that is protein …

  • Assuming anyone is still checking in here - I wonder what keeps people from posting. Here's what has kept me from posting: After I exercised some stock options in the client company that I've done work for the last 10 years and become part owner, I've found an extra incentive to make sure things go well there. We have had a major development project underway for the last year that has sucked my time. So work has kept me busy. The closest I've come to nanotechnology lately is that I started study…

  • Quote from lsuess: “So the Set described in the there discussed tooltip paper ( molecularassembler.com/Papers/MinToolset.pdf ) is not reversible in the bond-topology-state. ” Since the goal of the study did not include the additional burden of that requirement, I am not surprised. Efficient reversibility would see a longer-term goal. Quote from lsuess: “I made a 3D model for visualizing the qualitative progression of the energy wells that is necessary for a energetically reversible mechanosynthe…